Two-Variance-Component Model Improves Genetic Prediction in Family Datasets
نویسندگان
چکیده
منابع مشابه
Two-Variance-Component Model Improves Genetic Prediction in Family Datasets.
Genetic prediction based on either identity by state (IBS) sharing or pedigree information has been investigated extensively with best linear unbiased prediction (BLUP) methods. Such methods were pioneered in plant and animal-breeding literature and have since been applied to predict human traits, with the aim of eventual clinical utility. However, methods to combine IBS sharing and pedigree in...
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ژورنال
عنوان ژورنال: The American Journal of Human Genetics
سال: 2015
ISSN: 0002-9297
DOI: 10.1016/j.ajhg.2015.10.002